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For instance, two recent studies have identified GPT2-mediated coupling of pyruvate production to glutamine catabolism in two different tissue types: PIK3CA-mutated colorectal cancer cells (Hao et al, 2016), and Ras- and p53-transformed YMAC cells (Smith et al, 2016)

OxLDL promotes macrophage recruitment and activation in the arterial wall, contributing to plaque formation

In addition to AGEs and AGE adducts, HMGB1 and A can bind RAGEs to activate the NF-B, ERK1/2, p38, JNK, PI3K, Janus kinase/signal transducers and activators of transcription (JAK/STAT) pathways, leading to neuronal cell death and neurodegeneration 112

Effects of dopamine D4 receptor-selective antagonists on motor hyperactivity in rats with neonatal 6-hydroxydopamine lesions

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DTPA diethylenetriamine pentaacetate SHNH succinimidyl 6- hydrazinium nicotinate hydrochloride HMPAO hexamethylpropylene amine oxime the antibody may be derivatized so that a radioisotope may be bound directly to it (see, e.g., Yoo et al